Careers

Culture

We look for outstanding individuals who want to join our team and help support our goal of translation RNAi as a new class of innovative medicines.

We offer a dynamic workplace environment that provides all employees with the opportunity to contribute to the success of the company.

People

You will have a vital part helping to achieve Phyzat’s vision: to deliver cures through RNAi for serious, life-threatening diseases with limited treatment options for patients and their caregivers.

If you would like to join our team at Phyzat, please take a look at the current vacancies below and contact us via email at human.resources@phyzat.com.

Vacancies

Job purpose and dimensions:
The jobholder will be part of the growing siRNA therapeutics team. He or she will lead a research group dedicated to siRNA targeted deliveryby providing scientific direction, instruction and guidance to expedite research projects and to achieve important project milestones. This is an outstanding opportunity to be a founding member and scientific leader of an early-stage, well funded, start-up company.

Principal accountabilities:
• Lead an siRNA targeted delivery group and to provide scientific guidance (1 technician and 1-2 scientist)
• Lead and/or support internal research activities by managing and supervising assigned projects
• Ensures effective characterization and profiling of siRNA tools, leads and potential clinical candidates
• Accountable for high quality state of the art in-vivo deliverymethods and siRNA formulations
• Establish new in-vitro assays based on project needs
• Interface with external scientists on scientific projects that are collaboration- or contract-based
• Provide regular updates in internal meetings and feed into external and internal presentations and reports. Contribute to patents, publications and technical reports used in regulatory filings
• Guide and train technical staff, support personal development
• Support strategy discussions if needed and the implementation thereof
• Assist in identification of future drug/product candidates
• Prepare progress/project updates as project leader or jointly with project heads and present them internally

Qualifications:
The applicants should have a PhD degree in Pharmaceutical Sciences, Biochemistry, Molecular Biology, or other related field and 3-5 years experience of applicable experience or an equivalent combination of education and experience. .

Recruitment process:
Those who wish to be considered should submit a CV, along with a covering letter detailing your interest and suitability for the post, to human.resources@phyzat.com. The closing date for applications is December22nd. It is envisaged that first interviews for the post will take place the lastweek of December.
Job purpose and dimensions:
The jobholder will be part of the growing siRNA therapeutics team. He or she will integrate a research group to support non-clinical drug discovery across oncology, degenerative diseases, and aging.

Principal accountabilities:
• Supportlab-based research to support non-clinical drug discovery across a wide variety of disease indications as part of the therapeutic siRNA unit
• Expected to function independently, managing mechanistic pharmacology research projects
• Expected to participate in team based in-vitro/in-vivo testing of the pharmacodynamic effects of potential drug candidates in support of novel drug discovery
• Expected to support the implemention, optimization, and standardizationof screening assays for lead identification and the characterization of drug candidates
• Expected to work collaboratively with others across multiple disciplines

Qualifications:
The applicants should have a PhD degree in Pharmacology, Biology, Cell Biology, Biochemistry, Molecular Biology, or other related field and 3-5 years experience of applicable experience or an equivalent combination of education and experience. A strong background in cell and molecular biology, tissue culture, bioinformatics is a prerequisite for this position. Familiarity with basic concepts of the cell, cell-cell signaling, and molecular biology are required.

Recruitment process:
Those who wish to be considered should submit a CV, along with a covering letter detailing your interest and suitability for the post, to human.resources@phyzat.com. The closing date for applications is December 22nd. It is envisaged that first interviews for the post will take place the lastweek of December.
To be opened soon
Job purpose and dimensions:
The jobholder will be part of the growing siRNA therapeutics team. He or she will integrate a research group to support non-clinical drug discovery across oncology, degenerative diseases, aging, and infectious diseases.

Principal accountabilities:
• Conduct lab-based research to support non-clinical drug discovery across a wide variety of disease indications as part of the therapeutic siRNA unit
• Expected to function independently, designing and executing mechanistic pharmacology research projects
• Expected to participate in team based in-vitro/in-vivo testing of the pharmacodynamic effects of potential drug candidates in support of novel drug discovery
• Expected to implement, optimize, and standardize screening assays for lead identification and the characterization of drug candidates
• Expected to work collaboratively with others across multiple disciplines

Qualifications:
The applicants should have a PhD or MSc degree in Pharmacology, Biology, Cell Biology, Biochemistry, Molecular Biology, or other related field and 3-5 years experience of applicable experience or an equivalent combination of education and experience. Expertise in performing basic scientific assays including: RNA/DNA extraction, and protein preparation, PCR & real time-PCR, western blot analysis, ELISA, flow cytometry/FACS are essential. A strong background in cell and molecular biology, tissue culture, is a prerequisite for this position.Good knowledge of English is preferred, as well as behavioral competences in communication and teamwork and organizational skills. The job will require a certain amount of occasional travelling to meet with projects partners.

Recruitment process:
Those who wish to be considered should submit a CV, along with a covering letter detailing your interest and suitability for the post, to human.resources@phyzat.com. The closing date for applications is December 15th. It is envisaged that first interviews for the post will take place the fourth week of December.
PHYZAT BIOPHARMACEUTICALS
Rua Damião de Góis, 389-A, 1º BB — 4050-227 Porto, Portugal | info@phyzat.com
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